Monitoring rapid chemical communication in the brain.

By D. L. Robinson, Andre Hermans, Andrew T. Seipel, R. Wightman. Chemical Reviews, 2008

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Hybrid carbon based nanomaterials for electrochemical detection of biomolecules (2017, background): “2 ng/g, n = 3, 2 measurement per patient, subst nigra, postmortem human Epinephrine Plays role in the rewarding system, sensitivity towards environmental stimuli and tonic regulation of the level of arousal Y 200 [265,268]”
Dopamine in motivational control: rewarding, aversive, and alerting (2010, background): “…pathways to a direct test and to discover their detailed properties, aided by recently developed tools that allow DA transmission to be monitored (Robinson et al., 2008) and controlled (Tsai et al., 2009; Tecuapetla et al., 2010; Stuber et al., 2010) with high spatial and temporal precision.”
A genetically-encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice (2018, methodology): “Fast-scan cyclic voltammetry (FSCV) is an electrochemical method that can measure changes in extracellular DA concentrations with 10 ms temporal resolution and 1 nM sensitivity (Robinson et al., 2008).”