Antibody against poly(ethylene glycol) adversely affects PEG‐asparaginase therapy in acute lymphoblastic leukemia patients

By J. Armstrong, G. Hempel, S. Koling, Linda S. Chan, T. Fisher, H. Meiselman, G. Garratty. Cancer, 2007

668 citations recorded by the source corpus.

Subfields: Pathology and Forensic Medicine, Public Health, Environmental and Occupational Health, Rheumatology

View Paper: https://www.semanticscholar.org/paper/99976be0b64e584e6ccb4cc80194bc336bebc29b

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1. E. Batrakova
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Citations in the corpus

• Aptamers as therapeutics (2010, background): “Antibodies to synthetic oligonucleotides are not generally observed, but have been seen for some oligonucleotide conjugation partners such as PEG 58 .”
• Exosomes as Drug Delivery Vehicles for Parkinson’s Disease Therapy (2015, background): “Furthermore, it was reported that 22%-25% healthy blood donors already have preexisting PEG antibodies due to the everyday exposure to PEG in cosmetics, food, etc [18, 19].”