The risk of colorectal cancer in ulcerative colitis: a meta-analysis

By J. Eaden, K. Abrams, J. Mayberry. Gut, 2001

3,000 citations recorded by the source corpus.

Subfields: Epidemiology, Genetics, Oncology

View Paper: https://www.semanticscholar.org/paper/9983ab019701baf021a706883746e7a5ce575413

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. M. Karin
2. T. Jess
3. L. Peyrin-Biroulet
4. Christine Rungoe
5. S. Grivennikov

In Genetics

1. M. Karin
2. T. Jess
3. L. Peyrin-Biroulet
4. Christine Rungoe
5. S. Shalapour

In Oncology

1. M. Karin
2. S. Grivennikov
3. S. Rose‐John
4. J. Scheller
5. T. Jess
6. J. Terzic
7. Eliad Karin
8. L. Peyrin-Biroulet

Citations in the corpus

• Noninvasive Markers in the Assessment of Intestinal Inflammation in Inflammatory Bowel Diseases: Performance of Fecal Lactoferrin, Calprotectin, and PMN-Elastase, CRP, and Clinical Indices (2008, background): “for colon cancer especially in UC patients from year 8 after diagnosis (51).”
• Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002) (2010, result): “This is lower than shown in a previous meta-analysis.”
• Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer (2017, background): “7% [14], while people suffering from Crohn’s disease have a 2.”
• Effect of 5-Aminosalicylate Use on Colorectal Cancer and Dysplasia Risk: A Systematic Review and Metaanalysis of Observational Studies (2005, background): “Cancers occur at a young age and the risk of cancer increases significantly with time, approaching 18% after 30 yr of disease (3).”
• Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. (2012, methodology): “Subsequently, pooled SIRs with 95% CIs across cohorts were calculated for (1) CRC overall, (2) CRC in women and men separately, (3) CRC according to age at IBD diagnosis, and (4) CRC in patients with extensive colitis.”
• IL-6 and STAT3 are required for survival of intestinal epithelial cells and development of colitis associated cancer (2009, background): “Long-standing UC predisposes to development of colitis-asso-ciated cancer (CAC), the major cause of death in UC patients (Eaden et al., 2001).”
• Meta-analyses of Colorectal Cancer Risk Factors (2013, result): “The non-modifiable risk factors of family history of CRC and IBD were both confirmed to have a positive association with CRC, as reported in the literature [155, 156].”