Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge

By Randall J. Brezski, O. Vafa, D. Petrone, S. Tam, G. Powers, M. H. Ryan, Jennifer L. Luongo, Allison Oberholtzer, D. Knight, R. Jordan. 2009

94 citations recorded by the source corpus.

Subfields: Molecular Biology, Radiology, Nuclear Medicine and Imaging

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. M. Kinder
2. A. Greenplate
3. Katharine D. Grugan
4. Keri L. Soring
5. Katharine Heeringa
6. Stephen G McCarthy
7. G. Bannish
8. Meredith Perpetua

Citations in the corpus

• Engineered Protease-resistant Antibodies with Selectable Cell-killing Functions* (2013, methodology): “We had previously generated antihinge antibodies that bind to cleaved IgGs but do not react with the intact IgG counterpart (8, 23).”