Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.

By J. Calderaro, G. Couchy, S. Imbeaud, G. Amaddeo, E. Letouzé, J. Blanc, C. Laurent, Yacine Hajji, D. Azoulay, P. Bioulac-Sage and 2 more. Journal of Hepatology, 2017

656 citations recorded by the source corpus.

Subfields: Hepatology, Pathology and Forensic Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/98f3c897c1d927cc6e321e5c1607736eea0bd46b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Hepatology

1. J. Llovet
2. V. Mazzaferro
3. Alejandro Forner1 , 2
4. Peter R. Galle
5. F. Piscaglia
6. J. Raoul
7. D. Sarkar
8. Saranya Chidambaranathan-Reghupaty

In Pathology and Forensic Medicine

1. V. Mazzaferro
2. Alejandro Forner1 , 2
3. J. Llovet

In Surgery

1. J. Llovet

Citations in the corpus

• EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. (2018, background): “Especially hepatocellular adenomas with ß-catenin mutations in exon 3 carry a high risk of transformation into HCC and need to be identified.(234,236) Beside morphological parameters of malignancy (see above) analysis for human telomerase reverse transcription (hTERT) mutations may help to diagnose ”
• Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification (2020, methodology): “G1 tumors were associated with a progenitor phenotype, G3 with macro-trabecular massive subtype and G4 with steatohepatitic subtype (Calderaro et al., 2017).”