Placebo Effects: Biological, Clinical and Ethical Advances
By D. Finniss, Ted J. Kaptchuk, F. Miller, F. Benedetti. The Lancet, 2010
1,162 citations recorded by the source corpus.
For many years, placebos have been conceptualised by their inert content and their use as controls in clinical trials and treatments in clinical practice. Recent research demonstrates that placebo effects are genuine psychobiological phenomenon attributable to the overall therapeutic context, and that placebo effects can be robust in both laboratory and clinical settings. Evidence has also emerged that placebo effects can exist in clinical practice, even if no placebo is given. Further promotion and integration of laboratory and clinical research will allow advances in the ethical harnessing of placebo mechanisms that are inherent in routine clinical care and the potential use of treatments to primarily promote placebo effects.
Subfields: Cognitive Neuroscience, Complementary and alternative medicine, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/987ef58556ed9ac9813c5350135f9c3618df9321
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Citations in the corpus
- Constructing drug effects: A history of set and setting (2017, background): “…which focuses on questions of set and setting and controls for a variety of factors which shape set and setting, studying them much in the same way in which some investigators working in the placebo field control and measure various factors which shape placebo response (Finniss et al., 2010).”
- Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial (2011, result): “reported increased placebo response in endoscopic remission, histological remission, and clinical benefit (defined as response, improvement or clinical remission), in studies with more than three visits, compared with studies with three or fewer visits. It is possible that a high number of clinic vi”
- A Systematic Review and Meta-analysis (2011, neutral): “In addition, the placebo concept is controversially debated.(6,7,14) Certainly, the definition of placebo used in this systematic review is strict and conservative, especially regarding inertness.”