THE “GREAT OBSTETRICAL SYNDROMES” ARE ASSOCIATED WITH DISORDERS OF DEEP PLACENTATION
By I. Brosens, R. Pijnenborg, L. Vercruysse, Roberto Romero. American Journal of Obstetrics and Gynecology, 2010
1,437 citations recorded by the source corpus.
Defective deep placentation has been associated with a spectrum of complications of pregnancy including preeclampsia, intrauterine growth restriction, preterm labor, preterm premature rupture of membranes, late spontaneous abortion and abruption placentae. The disease of the placental vascular bed that underpins these complications is commonly investigated with targeted biopsies. In this review, we critically evaluate the biopsy technique to summarize the salient types of defective deep placentation and propose criteria for the classification of defective deep placentation into 3 types based on the degree of restriction of remodelling and the presence of obstructive lesions in the myometrial segment of the spiral arteries.
Subfields: Obstetrics and Gynecology, Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/97346a9f0d91e526f442f859956b300d57efd138
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In Obstetrics and Gynecology
In Pediatrics, Perinatology and Child Health
Citations in the corpus
- Pathophysiology of placental‐derived fetal growth restriction (2018, background): “Obstructive lesions in the myometrial segment of spiral bed arteries have been found in 70% of the FGR cases associated with preeclampsia.(46) Noninfectious villitis, also called villitis of unknown etiology (VUE), has been described as a pattern of placental injury occurring predominantly in”
- The role of aspirin dose on the prevention of preeclampsia and fetal growth restriction: systematic review and meta‐analysis (2017, positive): “However, the finding that therapy is effective only when treatment is initiated at 16 weeks is compatible with the knowledge that certainly severe PE, preterm PE, and FGR are associated with impaired placentation; in normal pregnancies the physiological transformation of uterine spiral arteries is c”