Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a…

By S. Mehta, J. Tanguay, J. Eikelboom, S. Jolly, C. Joyner, C. Granger, D. Faxon, H. Rupprecht, A. Budaj, Á. Avezum and 13 more. The Lancet, 2010

843 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine

View Paper: https://www.semanticscholar.org/paper/9729878ecfb6106329127fe9159780fa868535ff

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. G. Fonarow
2. P. O'Gara
3. J. Halperin
4. M. Mack
5. Hani Jneid
6. L. Fleisher
7. Judith Hochman
8. Allan S. Jaffe

Citations in the corpus

• ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. (2012, positive): “should be given instead.(115) Clopidogrel has not been evaluated against placebo in any large-outcome study in the setting of primary PCI, but a higher”
• 2018 ESC/EACTS Guidelines on myocardial revascularization. (2019, neutral): “When potent P2Y12 receptor inhibitors are contraindicated or are not available, clopidogrel should be given for primary PCI instead.(724) The value of pre-treatment with ticagrelor was addressed in the ATLANTIC (Administration of Ticagrelor in the Cath Lab or in the Ambulance for New STElevation Myo”
• 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (2014, background): “Loading and short-term maintenance doses of clopidogrel were studied in CURRENT–OASIS (Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent Events– Organization to Assess Strategies in Ischemic Syndromes) 7, which demonstrated a potential benefit of higher-dose clopidogrel (600-mg loading dose”
• 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. (2016, background): “, 2010 (37) 20817281 Aim: To assess the efficacy and safety of standard vs.”
• 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. (2013, positive): “A 600-mg loading dose of clopidogrel is preferred to a 300-mg loading dose, given the more extensive and rapid platelet inhibition achieved with the higher dose, as well as the beneficial effects reported in a CURRENT-OASIS 7 subgroup analysis.(259) The underpowered ARMYDA-6 MI (Antiplatelet Therapy”