Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review.

By Jessica Howard-Anderson, Patricia A. Ganz, J. Bower, A. Stanton. Journal of the National Cancer Institute, 2012

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Cancer treatment and survivorship statistics, 2014 (2014, background): “In addition, treatment with chemotherapy can lead to impaired fertility and premature menopause, which increases the risk of osteoporosis.(34) Anthracyclines and HER2-targeted drugs can lead to cardiomyopathy and congestive heart failure.”
Cancer treatment and survivorship statistics, 2016 (2016, background): “In addition, treatment with chemotherapy can lead to impaired fertility and premature menopause, which increase the risk of osteoporosis.(34) Chemotherapy with taxanes often leads to neuropathy, which can persist long after treatment ends.”
American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline (2016, positive): “Younger breast cancer patients can be particularly vulnerable to the physical, emotional, and psychosocial late effects of treatment because of the aggressiveness of their disease, the intensity of the treatment plan,(47,187) and their younger age, when a cancer diagnosis is not as common or is unex”
Global Cancer in Women: Burden and Trends (2017, background): “Younger breast cancer patients may have treatment-related side effects, such as impaired fertility or premature menopause (38).”