Translating the Diabetes Prevention Program into the Community The DEPLOY Pilot Study

By R. Ackermann, Emily A. Finch, E. Brizendine, Honghong Zhou, D. Marrero. American Journal of Preventive Medicine, 2008

670 citations recorded by the source corpus.

Background The Diabetes Prevention Program (DPP) found that an intensive lifestyle intervention can reduce the development of diabetes by more than half in adults with prediabetes, but there is little information about the feasibility of offering such an intervention in community settings. This study evaluated the delivery of a group-based DPP lifestyle intervention in partnership with the YMCA. Methods This pilot cluster-randomized trial was designed to compare group-based DPP lifestyle intervention delivery by the YMCA to brief counseling alone (control) in adults who attended a diabetes risk-screening event at one of two semi-urban YMCA facilities and who had a BMI ≥24 kg/m2, ≥2 diabetes risk factors, and a random capillary blood glucose of 110–199 mg/dL. Multivariate regression was used to compare between-group differences in changes in body weight, blood pressures, HbA1c, total cholesterol, and HDL-cholesterol after 6 and 12 months. Results Among 92 participants, controls were more often women (61% vs 50%) and of nonwhite race (29% vs 7%). After 6 months, body weight decreased by 6.0% (95% CI=4.7, 7.3) in intervention participants and 2.0% (95% CI=0.6, 3.3) in controls (p<0.001; difference between groups). Intervention participants also had greater changes in total cholesterol (−22 mg/dL vs +6 mg/dL controls; p<0.001). These differences were sustained after 12 months, and adjustment for differences in race and gender did not alter these findings. With only two matched YMCA sites, it was not possible to adjust for potential clustering by site. Conclusions The YMCA may be a promising channel for wide-scale dissemination of a low-cost approach to lifestyle diabetes prevention.

Subfields: Endocrinology, Diabetes and Metabolism

View Paper: https://www.semanticscholar.org/paper/96981c5f096d5764587b666f847d9402fe76c8d2

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In Endocrinology, Diabetes and Metabolism

Citations in the corpus

Standards of Medical Care in Diabetes—2012 (2011, background): “Group delivery of the DPP intervention in community settings has the potential to be significantly less expensive while still achieving similar weight loss (46).”
Standards of Medical Care in Diabetes—2013 (2012, background): “Group delivery of the DPP intervention in community settings has the potential to be significantly less expensive while still achieving similar weight loss (52).”
Successful behavior change in obesity interventions in adults: a systematic review of self-regulation mediators (2015, background): “However, so far, randomized controlled trials evaluating the effectiveness of programs that target lifestyle behavior have shown mixed effects and, if effective, they have generally resulted in only small changes in target behaviors [11-15].”
Diabetes in Older Adults (2012, background): “Preventive strategies that can be efficiently implemented in clinical settings and in the community have been developed and evaluated (23), but as yet there has been little focus on older adults in these translational studies.”
Standards of Medical Care in Diabetes—2014 (2013, background): “expensive while still achieving similar weight loss (58).”