Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues

By Y. Murakami, T. Yasuda, K. Saigo, T. Urashima, H. Toyoda, T. Okanoue, K. Shimotohno. Oncogene, 2006

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Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. (2007, background): “The lowest levels of microRNA expression are seen in very poorly differentiated tumors (42).”
microRNAs as oncogenes and tumor suppressors. (2007, background): “In contrast, miR-199a*, miR-195, miR-199a, miR-200a, and miR- 125a were underexpressed in HCC tissues (Murakami et al., 2006).”
MicroRNA signatures in human ovarian cancer. (2007, background): “recently shown down-modulated in other tumors, as hepatocellular carcinoma (36); and miR-140 , deleted in ovarian carcinoma (24).”
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. (2007, methodology): “(37) was done using a two-color approach, with a mixture of five human cell lines as reference.”
MicroRNA (miRNA) in cancer (2015, neutral): “[21,22,65-68].”
MicroRNA-cancer connection: the beginning of a new tale. (2006, background): “Cancer-specific miRNA fingerprints were identified in every type of analyzed cancer, including B-CLL (10), breast carcinoma (11), primary glioblastoma (12), hepatocellular carcinoma (13), papillary thyroid carcinoma (14), lung cancer (15–17), gastric carcinoma, colon carcinoma (18), and endocrine pa”