The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.
By I. Hellström, J. Raycraft, M. Hayden-Ledbetter, J. Ledbetter, Michèl Schummer, M. McIntosh, C. Drescher, N. Urban, K. Hellström. Cancer Research, 2003
771 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/95a7bca1eb5529d87fbe925756e1185885c38ff6
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Citations in the corpus
- The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass. (2008, methodology): “We selected a panel of serum and urine biomarkers shown to be elevated in patients with ovarian cancer and which may complement the sensitivity and specificity of CA125 [12–18].”
- Methods of Microarray Data Analysis III (2003, methodology): “K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH (2002) Gene expression profiling predicts clinical outcome of breast cancer.”
- Mass Spectrometry as a Diagnostic and a Cancer Biomarker Discovery Tool (2004, background): “Despite this reasonable hypothesis, very few cancer biomarkers have been discovered by using this approach (26, 27).”
- A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. (2009, background): “As well, HE4 is not elevated in many common benign gynecologic and medical conditions where CA125 is elevated [22].”