Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.

By A. Payne, D. B. Hales. Endocrine reviews, 2004

1,748 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/957b61546c2412d68eff71e80a3ea1502fc8e0a6

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Citations in the corpus

• Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. (2008, background): “Relative enzyme levels were quantified using the following antibodies at the indicated dilutions: rabbit polyclonal CYP17A1 (1:1,500) and rabbit polyclonal StAR (1:5,000) were both kindly donated by Dr. Hales (University of Illinois at Chicago, Chicago, IL; ref.”
• Leydig cells: formation, function, and regulation† (2018, background): “Four steroidogenic enzymes are involved in testosterone biosynthesis from cholesterol: Cytochrome P450 Family 11 Subfamily A1 (CYP11A1), 3β-hydroxysteroid dehydrogenase/ 5 → 4 isomerase (3β-HSD), CYP17A1, and 17β-HSD3 [50, 51].”