Role of reactive oxygen species in the pathophysiology of human reproduction.

By A. Agarwal, R. Saleh, M. Bedaiwy. Fertility and Sterility, 2003

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Antioxidants and poultry semen quality (2011, background): “Physiology of ROS Poor sperm quality has been linked to the excessive production of ROS as a result of lipid peroxidation in semen (Gomez et al., 1998; Agarwal et al., 2003).”
Effect of Oxidative Stress on Male Reproduction (2014, background): “In a study conducted by Agarwal et al [24], it was reported that the production of ROS by human spermatozoa increased significantly when spermatozoa were exposed to repeated cycles of centrifugation.”
Role of Vitamin E in Counteracting Oxidative Stress in Poultry (2013, background): “These ROS are involved in many physiological functions of spermatozoa, however, excessive production of the same may result in oxidative stress (Agarwal et al., 2003).”
Impacts of Oxidative Stress and Antioxidants on Semen Functions (2010, background): “The imbalance between the production of reactive oxygen species (ROS) and a biological systems ability to readily detoxify the reactive intermediates or easily repair the resulting damage is known as oxidative stress [8].”