Mechanism of shape determination in motile cells

By K. Keren, Zachary Pincus, Greg M. Allen, Erin L. Barnhart, G. Marriott, A. Mogilner, Julie A. Theriot. Nature, 2008

742 citations recorded by the source corpus.

Subfields: Cell Biology, Ecology, Evolution, Behavior and Systematics, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/9515bd24ae0788d7450bef2ec383f4b5bf1f0026

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In Cell Biology

In Ecology, Evolution, Behavior and Systematics

In Radiology, Nuclear Medicine and Imaging

David A. Weitz

Citations in the corpus

In vitro cell migration and invasion assays. (2013, background): “Common to all migration modes is the actomyosin cytoskeleton-mediated change of the cell body shape [15].”
Hydrodynamics of soft active matter (2013, background): “…a nonlinear way (Mogilner and Oster, 1999; Prost et al., 2007).5 The force-dependent treadmilling is essential for many cellular processes such as cell migration or cell adhesion and a full description including these effects in the active gel theory has not yet been proposed (Keren et al., 2008).”
Actin dynamics, architecture, and mechanics in cell motility. (2014, background): “The exponent w is positive for keratocytes, between 6 and 8, and was determined independently by aspect ratio observations and force measurements (118, 152).”
Mechanical induced wounds in fish – a review on models and healing mechanisms (2020, background): “filaments comprises an important component of the cytoskeleton of individual keratocyte cells (Keren et al. 2008; Elliott 2011).”
Cell mechanics and the cytoskeleton (2010, neutral): “What is needed now are more process-level models that connect the cytoskeleton with the plasma membrane or other physical boundary conditions and provide an understanding of cellular behaviours that depend on membrane–cytoskeleton interactions, as in a recent study describing shape variations in mot”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, neutral): “Theoretical models developed for the dynamic cell protrusions have been reviewed extensively [1029, 1030, 1031, 1045, 1032, 1036, 1037, 1038, 1039, 1040, 1041, 1042, 1043, 1044, 1018].”
Physical forces during collective cell migration (2009, background): “The single adherent cell moves by the action of two synchronized cycles, one involving extension and contraction of its cytoskeleton and the other involving formation and detachment of its adhesion”