Clonal evolution in cancer

By J. Salk. 2010

1,500 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/94b1b9f486b8ad5d126c6e10ccee31563fabfaa6

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Citations in the corpus

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data (2014, methodology): “We compared accuracy of detection of CNA and LOH events using TITAN (run once each for a fixed number of clusters ranging from one to five), APOLLOH (A) (Ha et al. 2012), Control-FREEC (CF) (Boeva et al. 2012), and BIC-seq (B) (Xi et al. 2011).”
Cancer Cell Metabolism: One Hallmark, Many Faces (2012, background): “The continuous evolution in our understanding of cancer cell biology has served to demonstrate that cancer is a remarkably complex and heterogeneous collection of diseases (1).”
Cancer Evolution: Mathematical Models and Computational Inference (2014, background): “…al. 2013; Klein 2013; Junttila and de Sauvage 2013; Burrell et al. 2013; Meacham and Morrison 2013; Almendro et al. 2013; Aparicio and Caldas 2013; Greaves and Maley 2012; Marusyk et al. 2012; Caldas 2012; Podlaha et al. 2012; Lambert et al. 2011; Michor and Polyak 2010; Salk et al. 2010; Bowtell…”
The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? (2015, unknown): “…advanced genome sequencing has demonstrated that cancer within a single patient is a heterogeneous mixture of genetically distinct sub-clones that arise through branching evolution (Greaves and Maley, 2012; Burrell et al., 2013) and seed different parts of a single tumor (Gerlinger et al., 2012).”
The causes and consequences of genetic heterogeneity in cancer evolution (2013, background): “In a heterogeneous glioblastoma multiforme cell population harbouring mosaic amplification of EGFR and PDGFRA, combined inhibition of both kinases was necessary to attenuate PI(3)K pathway activity in vitro(48).”
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution. (2015, background): “Clonal mutations, occurring on the trunk of a tumor’s phylogenetic tree, are early events, whereas subclonal events, occur- ring on the branches, reflect later events (Campbell et al., 2010; Gerlinger et al., 2012; Greaves and Maley, 2012; Landau et al., 2013).”
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia (2013, unknown): “These mutations were likely acquired either before or during themost recent complete selective sweep.”
A Big Bang model of human colorectal tumor growth (2015, background): “Every CNA was associated to a binary string, indicating its presence (1) or absence (0) in each sampled gland.”