Mannose-Binding Lectin Binds to a Range of Clinically Relevant Microorganisms and Promotes Complement Deposition

By O. Neth, D. Jack, A. Dodds, H. Holzel, N. Klein, M. Turner. Infection and Immunity, 2000

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Allergic bronchopulmonary aspergillosis in cystic fibrosis--state of the art: Cystic Fibrosis Foundation Consensus Conference. (2003, background): “as laminin, fibronectin, and fibrinogen; and mannose-binding lectin efficiently, as well as C3 [60–64].”
The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120 (2002, background): “Certain pathogens that are heavily mannosylated, such as yeast, are cleared rapidly by this mechanism (39).”
Innate Immunity to Mycobacterium tuberculosis (2002, background): “MBL recognizes carbohydrate configurations on a wide variety of pathogens (150) and induces phagocytosis”
Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis (2009, background): “fumigatus conidia by macrophages and neutrophils (2, 3, 120, 144).”
The role of mannose-binding lectin in health and disease. (2003, methodology): “We have used flow cytometry to study MBL binding to a range of clinically relevant pathogens isolated from immunocompromised children and found large differences.(30) Some organisms such as Candida albicans, -haemolytic Group A Streptococci and Staphylococcus aureus have consistently exhibited high ”