Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation.

By M. Premanathan, K. Karthikeyan, K. Jeyasubramanian, G. Manivannan. Nanomedicine: Nanotechnology, Biology and Medicine, 2011

1,086 citations recorded by the source corpus.

Subfields: Biotechnology, Materials Chemistry, Pharmacology

View Paper: https://www.semanticscholar.org/paper/92ffcda07aefab7263e3e4610483fab1b3adca33

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

Citations in the corpus

Ecotoxicity of manufactured ZnO nanoparticles--a review. (2013, methodology): “…bacterium such as S. aureus is more susceptible to ZnO NP toxicity than Gram-negative bacteria such as E. coli and Pseudomonas aeruginosa (Premanathan et al., 2011), which may be attributed to the differences in bacteria’s cell membrane structure that controls the toxicant’s access to…”
Comparison of TiO2 and ZnO nanoparticles for photocatalytic degradation of methylene blue and the correlated inactivation of gram-positive and gram-negative bacteria (2013, background): “The greater sensitivity of grampositive bacteria to ZnO nanoparticles in comparison to gram-negative bacteria has been commonly observed (Tayel et al. 2011; Sawai et al. 1995; Adams et al. 2006; Premanathan et al. 2011).”
Zinc Oxide Nanoparticles: Synthesis, Antimicrobial Activity and Food Packaging Applications (2012, methodology): “Similarly, ZnO nanoparticles have exhibited a preferential ability to kill human myeloblastic leukemia cells (HL60) compared to healthy eukaryotic cells (normal peripheral blood mononuclear cells) (Premanathan et al., 2011).”
Antimicrobial activity of metal oxide nanoparticles against Gram-positive and Gram-negative bacteria: a comparative study (2012, positive): “Our finding is in agreement with Premanathan et al, who reported that the ZnO nanoparticle effect is more pronounced against Gram-positive bacterial strains than Gram-negative bacterial strains.(22) Furthermore, previous studies have shown that the smaller the ZnO particle size, the greater the effi”
Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications (2021, background): “Several studies suggest that Zn2+ ions released to the medium from the ZnO-NPs are the main contributor of the antibacterial activity of the respective nanoparticles [107,108].”
Properties of Zinc Oxide Nanoparticles and Their Activity Against Microbes (2018, background): “[66] have reported the toxicity of zinc oxide nanoparticles against prokaryotic and eukaryotic cells.”
Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species (2012, positive): “ZnO NPs exhibited a preferential ability to kill human myeloblastic leukemia cells (HL60) as compared with normal peripheral blood mononuclear cells.(9) Hanley et al(7) also observed that ZnO NPs exhibit a strong preferential ability to kill cancerous T cells compared with normal cells.”