Inflammation and Stroke: Putative Role for Cytokines, Adhesion Molecules and iNOS in Brain Response to Ischemia

By G. Zoppo, I. Ginis, J. Hallenbeck, C. Iadecola, Xinkang Wang, G. Feuerstein. Brain Pathology, 2000

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Pathophysiology of Cerebral Ischemia and Brain Trauma: Similarities and Differences (2004, background): “Following cerebral ischemia and endothelial damage, activated platelets interact with the endothelium and facilitate its conversion from an anti-inflammatory, antithrombotic state to a pro-inflammatory, pro-thrombotic state (del Zoppo et al., 2000).”
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke (2009, background): “, it is also associated with severe immune dysregulation, including simultaneous activation of cerebral inflammatory signalin”
Inflammatory processes in Alzheimer's disease. (2007, neutral): “…generation have been described in several brain pathologies including demyelinating diseases (Willenborg et al., 1999a, b), cerebral ischemia (del Zoppo et al., 2000), AIDS dementia (Hori et al., 1999), amyotrophic lateral sclerosis (Almer et al., 1999), and AD (Wallace et al., 1997; Weldon et…”