Climate change factors and Aspergillus flavus: effects on gene expression, growth and aflatoxin production
By Á. Medina, Alicia Rodríguez, Y. Sultan, Naresh Magan. 2015
112 citations recorded by the source corpus.
The objectives of this study were to obtain scientific data on the impact that interactions between water stress (water activity (aw); 0.97, 0.95, 0.92), temperature (34, 37 °C) and CO2 exposure (350, 650, 1000 ppm) may have on the growth, gene expression of biosynthetic genes (aflD, aflR), and phenotypic aflatoxin B1 (AFB1) production by a type strain of Aspergillus flavus on a conducive medium. The study showed that while aw affected growth there was no statistically significant effect of temperature or CO2 exposure. The effect of these interacting factors on aflD and aflR gene expression showed that at 34 °C there was maximum relative expression of aflD under the control conditions (34 °C, 350 ppm) with a decrease in expression with elevated CO2 and water stress. For aflR expression at 34 °C, there was a significant increase in expression, but only at 0.92 aw and 650 ppm CO2. However, at 37 °C, there was a significant increase in expression of both aflD and aflR at 0.95 and 0.92 aw and 650 and 1000 ppm...
Subfields: Ecology, Evolution, Behavior and Systematics, Health, Toxicology and Mutagenesis, Plant Science
View Paper: https://www.semanticscholar.org/paper/92e84ecb2163a6ef207ad80d205ce6cc6d631ead
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In Health, Toxicology and Mutagenesis
In Plant Science
Citations in the corpus
- Climate change, food security and mycotoxins: Do we know enough? (2017, background): “Studies of the relative expression of the biosynthetic genes in the aflatoxin pathway also corroborated these findings (Medina et al., 2015a).”