Antifungal Resistance of Candidal Biofilms Formed on Denture Acrylic in vitro

By J. Chandra, P. Mukherjee, S. Leidich, F. Faddoul, L. Hoyer, L. Douglas, M. Ghannoum. Journal of dentistry research, 2001

603 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins (2002, methodology): “Biofilm drug resistance is a phenomenon consistently expressed across model microbial systems (6, 13, 14, 21, 29) and likely to be of great clinical relevance (16).”
Biofilm Formation by the Fungal PathogenCandida albicans: Development, Architecture, and Drug Resistance (2001, methodology): “albicans cells are highly resistant to antifungal agents such as fluconazole, nystatin, amphotericin B, and chlorhexidine (11), similar to previous observations reported for catheter-associated C.”
Candida Biofilms: an Update (2005, background): “In addition, Chandra and colleagues reported that a progression of drug resistance was associated with an increase in the metabolic activity of the developing biofilm and not with a lower growth rate, which clearly indicates that drug resistance develops over time, coincident with biofilm maturation”