Inaugural Article: Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1

By H. Kim. 2005

356 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9249a3b30e37890024e20fcf15ceb72b27b5b0ad

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Yaqiu Wang
2. T. Kanneganti
3. F. Llambi

Citations in the corpus

• From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways (2021, background): “Cytosolic cytochrome C is sensed by APAF1, which then forms the apoptosome with CASP9, the initiator caspase of the intrinsic apoptotic pathway [42].”
• Cell Death Signaling. (2015, background): “For example following cytochrome c binding to APAF1, the failure to replace hydrolyzed dADP by exogenous dATP triggers nonfunctional aggregation and irreversible inactivation of APAF1 (Kim et al. 2005).”