Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

By D. J. Cavanaugh, Hyosang Lee, Liching Lo, S. Shields, M. Zylka, A. Basbaum, David J. Anderson. Proceedings of the National Academy of Sciences of the United States of America, 2009

691 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Physiology, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/923f0bb624c653962977b0e2fc77ac10b613a5dd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. D. Bautista
2. D. Julius
3. A. Basbaum
4. Grégory Scherrer
5. Arne May
6. Clifford J. Woolf
7. Ardem Patapoutian
8. R. Medzhitov

In Physiology

1. D. Julius
2. D. Bautista
3. A. Basbaum
4. Grégory Scherrer
5. Arne May
6. R. Medzhitov
7. Clifford J. Woolf

In Sensory Systems

1. D. Julius
2. D. Bautista
3. A. Basbaum
4. Grégory Scherrer
5. Clifford J. Woolf
6. Ardem Patapoutian
7. Arne May
8. R. Medzhitov

Citations in the corpus

• TRP channels and pain. (2013, background): “TRPM8 is robustly expressed by ∼15% of all somatosensory neurons encompassing mostly small-diameter, unmyelinated C-fibers, as well as a minor cohort of lightly myelinated Aδ fibers.”
• Cellular and Molecular Mechanisms of Pain (2009, positive): “Finally, it is noteworthy that capsaicin-treated mice lacking the central terminals of TRPV1-expressing fibers show intact behavioral responses to cool and noxious cold stimuli (Cavanaugh et al., 2009).”