Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint.

By C. Rieder, H. Maiato. Developmental Cell, 2004

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. (2008, background): “Duration of Mitotic Arrest Does Not Dictate Fate It is widely assumed that the duration of mitotic arrest dictates subsequent cell fate (Masuda et al., 2003; Rieder and Maiato, 2004; Weaver and Cleveland , 2005; Tao et al., 2005).”
How Taxol/paclitaxel kills cancer cells (2014, background): “Still other studies have found that the state of the mitotic checkpoint does not affect this sensitivity (Rieder and Maiato, 2004; Weaver and Cleveland, 2005; Yamada and Gorbsky, 2006; Ryan et al., 2012).”