Mitochondrial DNA as a marker of molecular diversity: a reappraisal

By Nicolas Galtier, B. Nabholz, Sylvain Glemin, G. Hurst. Molecular Ecology, 2009

1,110 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/91c7647104456d88eed03763809a31a966e29cb3

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In Ecology, Evolution, Behavior and Systematics

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Citations in the corpus

Review: genetic diversity of local and exotic cattle and their crossbreeding impact on the quality of Indonesian cattle. (2015, background): “…marker that is very useful to study the origin, genetic diversity and descendant differentiation because it has unique characteristics inherited from the female broodstock, the fast rate of evolution and the less level of recombination (Bailey et al. 1996; Liu et al. 2006; Galtier et al. 2009).”
Capturing single-copy nuclear genes, organellar genomes, and nuclear ribosomal DNA from deep genome skimming data for plant phylogenetics: A case study in Vitaceae (2021, background): “However, mtDNA in general has not been a highly informative phylogenetic marker at the genus level (Galtier et al., 2009; Spooner et al., 2020a, 2020b)due to the low sequence substitution rate.”
DNA Barcodes for Marine Biodiversity: Moving Fast Forward? (2010, background): “Reasons for choosing mitochondrial (mtDNA) over nuclear DNA include uniparental inheritance (in a majority of animal phyla), high evolutionary rate, lack of introns, large copy numbers in every cell, and limited recombination (but see [25]).”
Complete mitochondrial genomes and a novel spatial genetic method reveal cryptic phylogeographical structure and migration patterns among brown bears in north‐western Eurasia (2013, background): “Inference from mtDNA is limited by the fact that the molecule represents a single marker and cannot inform about processes affecting the paternal lineages (for other problems related to mtDNA, see e.g. Galtier et al., 2009).”
When cryptic diversity blurs the picture: a cautionary tale from Iberian and North African Podarcis wall lizards (2011, background): “…are based on a single genetic marker, potentially suffering from the limitations that are associated with such an approach (Zhang & Hewitt, 2003; Galtier et al., 2009), the extensive background information previously obtained for this particular system (i.e. general concordance with nuclear…”
Phylogeography unplugged: comparative surveys in the genomic era (2014, background): “Recent years have seen several papers challenging the utility of mtDNA, citing limited examples of selective sweeps, non-uniparental inheritance, and non-clonality (e.g., Bazin et al. 2006, Galtier et al. 2009).”