Meta-Analysis: Obesity and the Risk for Gastroesophageal Reflux Disease and Its Complications

By H. Hampel, N. Abraham, H. B. EL‐SERAG. Annals of Internal Medicine, 2005

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The medical complications of obesity. (2006, background): “A recent meta-analysis found a significant association between obesity and the risk for GORD symptoms, erosive oesophagitis and oesophageal adenocarcinoma.(104)”
Body-mass index and symptoms of gastroesophageal reflux in women. (2006, positive): “L’association positive entre un indice de masse corporelle (IMC = (poids en kg)/(taille en m)2) élevé et les symptômes de RGO a déjà été retrouvée dans plusieurs études [5].”
Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. (2007, background): “Obesity in the absence of asthma causes physiologic impairments in lung function, including reduction in lung volumes (35), chest wall restriction (36), and increased oxygen cost of breathing (37), and contributes to comorbid conditions such as gastroesophageal reflux ( 38 , 39) and sleep apnea; the”
Morbidity and mortality associated with obesity. (2017, result): “study which analyzed nine different studies reported that there are statistically significant associations between BMI and GERD in six studies, significant associations of BMI with erosive esophagitis in six studies, and significant associations of BMI with gastric cardia adenocarcinoma in four stud”