High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2
By Steven Sanche, Y. Lin, Chonggang Xu, E. Romero-Severson, N. Hengartner, R. Ke. Emerging Infectious Diseases, 2020
1,399 citations recorded by the source corpus.
Severe acute respiratory syndrome coronavirus 2 is the causative agent of the ongoing coronavirus disease pandemic. Initial estimates of the early dynamics of the outbreak in Wuhan, China, suggested a doubling time of the number of infected persons of 6–7 days and a basic reproductive number (R0) of 2.2–2.7. We collected extensive individual case reports across China and estimated key epidemiologic parameters, including the incubation period (4.2 days). We then designed 2 mathematical modeling approaches to infer the outbreak dynamics in Wuhan by using high-resolution domestic travel and infection data. Results show that the doubling time early in the epidemic in Wuhan was 2.3–3.3 days. Assuming a serial interval of 6–9 days, we calculated a median R0 value of 5.7 (95% CI 3.8–8.9). We further show that active surveillance, contact tracing, quarantine, and early strong social distancing efforts are needed to stop transmission of the virus.
Subfields: Clinical Psychology, Economics and Econometrics, Modeling and Simulation
View Paper: https://www.semanticscholar.org/paper/914a3e04fee0f4b65e1b94c654c7a1755d5a8930
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In Clinical Psychology
Citations in the corpus
- Conspiracy theories as barriers to controlling the spread of COVID-19 in the U.S. (2020, background): “Because it is highly contagious, controlling the spread of the novel coronavirus COVID-19 requires widescale public adoption of preventive behaviors (Sanche et al., 2020).”
- Cell entry mechanisms of SARS-CoV-2 (2020, neutral): “Yet SARS-CoV-2 remains highly infectious (11, 12).”