Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies.
By M. Shibuya. Genes & cancer, 2011
1,531 citations recorded by the source corpus.
Subfields: Cancer Research, Cell Biology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/909951ebe78013e14d887b2b955b79fbde8c7db5
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In Cancer Research
In Molecular Biology
Citations in the corpus
- Angiogenic signaling pathways and anti-angiogenic therapy for cancer (2023, background): “VEGFR-3 (FLT-4) is a precursor protein with a molecular weight of 195 kDa, mainly expressed in lymphatic endothelial cells and mediates the activation of VEGF-C and VEGF-D, impelling lymphoid proliferation and metastasis of tumor.(86) VEGFR-3 is frequently over-expressed in metastatic CRC,(114) BC,(”