Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

By Jörn Dengjel, O. Schoor, R. Fischer, Michael Reich, M. Kraus, Margret Müller, Katharina Kreymborg, F. Altenberend, J. Brandenburg, H. Kalbacher and 4 more. Proceedings of the National Academy of Sciences of the United States of America, 2005

673 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Parasitology

View Paper: https://www.semanticscholar.org/paper/9066c2f078c0d6ec5ca8387a79aa706d37b2ae78

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. V. Deretic
2. Beth Levine
3. Judy H. Cho
4. Ramnik J. Xavier
5. N. Mizushima
6. Guido Kroemer
7. D. Klionsky
8. Douglas R. Green

In Immunology

1. Judy H. Cho
2. Beth Levine
3. V. Deretic

In Parasitology

1. Beth Levine
2. V. Deretic
3. Judy H. Cho
4. G. Hotamışlıgil
5. Guido Kroemer
6. N. Mizushima
7. D. Klionsky

Citations in the corpus

• Unveiling the roles of autophagy in innate and adaptive immunity (2007, background): “At least in certain contexts, autophagy promotes MHC class II presentation of cytosolic antigens [66] [67] [68] [69] [70] 70 .”
• Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis (2007, background): “In cells with low levels of endocytosis, such as epithelial cells, this is likely to be an important route for antigen presentation and immune surveillanc”
• NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation (2010, background): “As autophagy has been shown to be responsible for constitutive and efficient delivery of cytosolic proteins for MHC class II presentation in DC”
• The importance of immune gene variability (MHC) in evolutionary ecology and conservation (2005, neutral): “bacteria, nematodes, cestodes) [43,44].”