Combining Bioinformatics and Phylogenetics to Identify Large Sets of Single-Copy Orthologous Genes (COSII) for Comparative, Evolutionary and Systematic Studies: A Test Case in the Euasterid Plant…

By Feinan Wu, Lukas A. Mueller, D. Crouzillat, V. Pétiard, S. Tanksley. Genetics, 2006

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Development of COS genes as universally amplifiable markers for phylogenetic reconstructions of closely related plant species (2008, methodology): “…et al., 2004; Hughes et al., 2006) and large collections of high quality LCNG sets have been developed for selected taxa (e.g., Choi et al., 2006; Wu et al., 2006), the development of highly informative LCNG phylogenetic markers may still be an extremely time-consuming task, sometimes fraught…”
Wild Crop Relatives: Genomic and Breeding Resources (2011, methodology): “The same population has been used to develop a new molecular linkage map using conserved ortholog set (COS) and conserved ortholog set II (COSII) markers derived from a comparison of the tomato expressed sequence tag (EST) database against the entire Arabidopsis genome (Fulton et al. 2002b; Wu et al”
A Snapshot of the Emerging Tomato Genome Sequence (2009, background): “Most of the markers are conserved ortholog set (COS) markers (Fulton et al., 2002; Wu et al., 2006) derived from a comparison of Solanaceae ESTs against the entire Arabidopsis genome.”
Model legumes contribute to faba bean breeding (2010, background): “, 2005 and many others), although collinearity between large chromosomal blocks of markers across species separated by wider taxonomic distances has also been identified in a few cases (Lee et al., 2001; Wu et al., 2006).”