Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
By Kook Hwan Kim, Yeon Taek Jeong, Hyunhee Oh, Seong Hun Kim, Jae-min Cho, Yo-Na Kim, Su Sung Kim, Do Hoon Kim, K. Hur, Hyoung-Kyu Kim and 12 more. Nature Medicine, 2012
777 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/905d5eb420c0a31135514cf96a6bef5b98873b2f
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Citations in the corpus
- Insulin Resistance: From Mechanisms to Therapeutic Strategies (2021, background): “In addition, skeletal muscle-specific deletion of autophagy-related gene-7 (ATG-7) protected mice from diet-induced obesity and insulin resistance and was accompanied by increased fat oxidation and adipocyte browning [174].”
- Fatty acid trafficking in starved cells: regulation by lipid droplet lipolysis, autophagy and mitochondrial fusion dynamics (2015, background): “, lipase digestion of LDs) in mobilizing FAs are ambiguous (Kim et al., 2013; Smirnova et al., 2006; Wang et al., 2008).”