Lessons for management of anaphylaxis from a study of fatal reactions

By Pumphrey. Clinical and Experimental Allergy, 2000

1,062 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Increase in anaphylaxis-related hospitalizations but no increase in fatalities: An analysis of United Kingdom national anaphylaxis data, 1992-2012 (2015, methodology): “Acute, life-threatening systemic allergic reactions (anaphylaxis) can lead to cardiorespiratory arrest within minutes.(1) For those affected, the threat of further episodes can lead to significant lifestyle restrictions and psychological consequences.”
Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology (2014, background): “Nausea and vomiting may also be associated with anaphylaxis (22) (Fig.”
Update on food allergy. (2004, background): “In addition to variable expression of cutaneous, respiratory, and gastrointestinal symptoms, patients might have cardiovascular symptoms, including hypotension, vascular collapse, and cardiac dysrhythmias.(81) Curiously, serum b-tryptase levels are rarely increased in foodinduced anaphylaxis.”
Clinical features and severity grading of anaphylaxis. (2004, background): “The data here indicating an insignificant effect of increasing age on reaction severity in food anaphylaxis are also consistent with the fact that food anaphylaxis deaths have a younger median age of 22-24 years.(12) Alternatively, the younger age of food anaphylaxis deaths may simply represent the ”