Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

By K. Fisch. 2013

151 citations recorded by the source corpus.

This review discusses the biosynthesis of natural products generated by iterative hybrid polyketide synthases–non ribosomal peptide synthetases (PKS–NRPS) from fungi and bacteria, the programming of the enzymes and bioengineering approaches.

Subfields: Biotechnology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/903e42cf7d47301ca68c456952ae420378e0008d

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1. F. Licciardi
2. J. Mahillon
3. A. Gillis
4. Catherine Nannan
5. S. Caulier
6. C. Bragard

Citations in the corpus

• Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group (2019, background): “In some cases, mixed PKs pathways combine different types of PKSs or can even be associated with FASs or NRP synthetases (NRPSs) to form PKpeptide hybrid metabolites such as bacillaene, compactin, fusarin C or salinosporamide A (Moldenhauer et al., 2007; Hertweck, 2009; Fisch, 2013).”