GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

By K. Rossman, C. Der, J. Sondek. Nature reviews. Molecular cell biology, 2005

1,867 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8fd91b02ca9d45861a7f13155eb604f5d2746f6b

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In Molecular Biology

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Citations in the corpus

• GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo (2007, background): “The reader can find additional information about phenotypes of transgenic mice expressing Rho/Rac proteins and knockout animals lacking genes for Rho/Rac GEFs in recent review articles.(6,56,57)”
• GEFs and GAPs: critical elements in the control of small G proteins. (2007, background): “Indeed structural analysis has shown that the relative orientation of the PH domain toward the DH domain is completely different in various GEFs (Rossman et al., 2005).”