Early coagulopathy in multiple injury: an analysis from the German Trauma Registry on 8724 patients.
By M. Maegele, R. Lefering, N. Yucel, T. Tjardes, D. Rixen, T. Paffrath, C. Simanski, E. Neugebauer, B. Bouillon. Injury, 2007
725 citations recorded by the source corpus.
Subfields: Critical Care and Intensive Care Medicine, Hematology, Surgery
View Paper: https://www.semanticscholar.org/paper/8f847259db5356414ec65304386d9fc6c89c3bbe
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In Critical Care and Intensive Care Medicine
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Citations in the corpus
- Management of bleeding and coagulopathy following major trauma: an updated European guideline (2013, background): “About one-third of all bleeding trauma patients present with a coagulopathy upon hospital admission [4-7].”
- Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate (2010, background): “Introduction Coagulopathy has been shown to be present in approximately 25 to 35% of all trauma patients on admission to the emergency room (ER) [1,2].”
- The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition (2016, methodology): “Moreover, another retrospective analysis using the German Trauma Registry database, 16 including 17,200 multiply-injured patients, showed that the incidence of coagulopathy 17 increased with increasing volume of intravenous fluids administered pre-clinically [9].”
- Management of bleeding following major trauma: an updated European guideline (2010, methodology): “Seven studies showed better outcomes using a high FFP:RBC ratio [3,261-266] and two did not [250,267].”
- The coagulopathy of trauma: a review of mechanisms. (2008, background): “Trauma patients have a higher incidence of sepsis than the average critical care population, and in both trauma and sepsis patients an episode of coagulopathy results in a prothrombotic state(83) and a propensity to multiple organ failure.(14)”
- The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition (2019, background): “It has been shown that aggressive volume administration increased the incidence of secondary abdominal compartment syndrome (ACS) [324], damage-control laparotomy [322], coagulopathy [14], multiple organ failure [323], nosocomial infections [323], the number of blood as well as mass transfusions [31”