Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

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Curcumin: A Review of Its’ Effects on Human Health (2017, background): “The medicinal properties of turmeric, the source of curcumin, have been known for thousands of years; however, the ability to determine the exact mechanism(s) of action and to determine the bioactive components have only recently been investigated [2].”
Challenges in liver cancer and possible treatment approaches (2019, background): “Curcumin, a component of turmeric, has numerous biological effects in various diseases, including liver cancer [28].”
Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects (2019, background): “Curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BMC) are bioactive polyphenolic compounds identified in turmeric [14,15], which have been collectively referred to as curcuminoids (CCMs).”
Bactericidal Activity of Curcumin I Is Associated with Damaging of Bacterial Membrane (2015, background): “Curcumin I showed no toxic effect on human health even when taken at doses as high as 8 g day [18, 2].”
Carotenoids: biochemistry, pharmacology and treatment (2016, background): “Despite the lower bioavailability of curcumin, its therapeutic efficiency has been proven in different human diseases including CVDs, diabetes, cancer, arthritis, Crohn’s disease and neurological diseases (Anand et al., 2007; Gupta et al., 2013).”