Hypertrophic Cardiomyopathy Is Predominantly a Disease of Left Ventricular Outflow Tract Obstruction

By M. Maron, Iacopo Olivotto, A. Zenovich, Mark S. Link, N. Pandian, Jeffery T. Kuvin, S. Nistri, F. Cecchi, J. Udelson, B. Maron. Circulation, 2006

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Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine. (2014, methodology): “Outflow gradients are characteristically dynamic, with spontaneous variability influenced by altered myocardial contractility and loading conditions (2,4,11,16,21,39,40).”
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American Association for Thoracic Surgery, American Soci (2011, methodology): “The committee was composed of physicians and cardiac surgeons with expertise in HCM, invasive cardiology, noninvasive testing and imaging, pediatric cardiology, electrophysiology , and genetics.”
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines (2011, methodology): “For these reasons, stress echocardiography to tect or rule out CAD may be unreliable in HCM but may be eful to document the presence or magnitude of outflow tract struction generated by exercise (8) (Section 4.”