Metagenome—a challenging source of enzyme discovery

By P. Lorenz, C. Schleper. 2002

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How researchers see this paper

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Metagenomics: genomic analysis of microbial communities. (2004, background): “Exploiting the rich microbial biodiversity for enzyme and natural product discovery is an active research area that has been reviewed elsewhere (39, 45, 46, 65, 66, 77, 97, 104).”
Metagenomics: Application of Genomics to Uncultured Microorganisms (2004, background): “Functional screens have identified new enzymes (39, 52, 53, 67, 68, 72, 73, 88, 93, 104, 118, 122, 124, 144) and antibiotics (22, 23, 39, 61, 69, 91, 110, 118, 146) and other reagents in libraries from diverse environments.”
The metagenomics of soil (2005, methodology): “The same approach has been used to clone genes from soil communities that code for lipase”