Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

By M. Lauth, Åsa Bergström, T. Shimokawa, R. Toftgård. Proceedings of the National Academy of Sciences of the United States of America, 2007

781 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8e11b1bb8152d1f452a4273ecb74bb24f18f0d15

How researchers see this paper

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In Molecular Biology

1. Marcello Maggiolini
2. Rosamaria Lappano

Citations in the corpus

• G protein-coupled receptors: novel targets for drug discovery in cancer (2010, methodology): “The use of GLI inhibitors such as GANT58 and GANT61, which were capable of preventing tumour growth in vitro and in xenograft cancer model”
• Targeting cancer stem cell pathways for cancer therapy (2020, background): “617 The Wnt signaling pathway is associated with tumor development in breast cancer, 618 ovarian cancer, 619 esophageal squamous cell cancer, 620 colon cancer, 621 prostate cancer, 622 and lung cancer.”