Chronic thromboembolic pulmonary hypertension.

By W. Auger, P. Fedullo. Seminars in Respiratory and Critical Care Medicine, 2009

1,410 citations recorded by the source corpus.

The last 4 decades have witnessed dramatic changes in the treatment of patients with pulmonary hypertension. And with the advances in cardiothoracic surgical techniques, selected patients with chronic thromboembolic pulmonary hypertension (CTEPH) are afforded a surgical remedy for their disease. In the vast majority of these patients, surgical endarterectomy of chronic thromboemboli from the pulmonary vascular bed effectively treats even severe pulmonary hypertension, and as a result, the debilitating symptoms of right heart dysfunction. This article reviews the natural history of chronic thromboembolic disease and outline a suggested diagnostic approach to determine whether a patient with chronic thromboembolic disease might be an appropriate surgical candidate. Pulmonary thromboendarterectomy surgery, and the growing information on the use of pharmacotherapy in inoperable CTEPH, are also reviewed.

Subfields: Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/8dfe96d3323ddbe823485e16433b7885ef9465df

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In Pulmonary and Respiratory Medicine

1. G. Simonneau
2. N. Galiè

Citations in the corpus

• ESC Guidelines on the diagnosis and management of acute pulmonary embolism (2014, neutral): “(2013)).(412) ESC Guidelines Page 33 of 48”
• Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism (2008, background): “These patients are not candidates for embolectomy as they need specific pulmonary endarterectomy, which should be performed in specialized centres.(274) In summary, with current surgical techniques pulmonary embolectomy is a valuable therapeutic option in patients with highrisk PE in whom thrombolys”
• Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. (2012, methodology): “For these reasons, we no longer identify central disease as a selection factor for thromboendarterectomy in patients with CTEPH, and we emphasize that patients with CTEPH should be assessed by a team with expertise in the evaluation and management of pulmonary hypertension.(153,159,164-166)”
• Updated clinical classification of pulmonary hypertension. (2009, background): “An update for Groups 2, 3, and 4 will be published separately in the same issue of this supplement (66 – 68), providing some important adaptations regarding de fi nitions and management.”
• [2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism]. (2014, neutral): “(2013)).(412) ESC Guidelines Page 33 of 48”
• Pulmonary arterial hypertension (2013, background): “graphic findings in CTEPH are complete obstruction, band and webs as well as intimal irregularities [74].”