Why Nature Chose Selenium.

By H. Reich, R. Hondal. ACS Chemical Biology, 2016

708 citations recorded by the source corpus.

Subfields: Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/8de295b5ea2646b79ed804dc1777a5055ff9be22

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Nutrition and Dietetics

1. Elias S. J. Arnér
2. M. Conrad
3. F. Ursini
4. M. Maiorino

Citations in the corpus

• GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues (2017, positive): “The reaction catalyzed by selenoperoxidases is faster (68), due to the better nucleophilic character of selenium in the oxidative part of the catalytic cycle and the better electrophilicity in the reductive part (90).”
• Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. (2017, positive): “These findings support the notion that the critical advantage of selenolate- versus thiolate-based catalysis lies in its resistance to overoxidation, a notion that has been previously postulated based on studies using recombinant proteins (Reich and Hondal, 2016).”