Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants.

By H. Zreiqat, C. Howlett, A. Zannettino, P. Evans, G. Schulze-Tanzil, C. Knabe, M. Shakibaei. Journal of Biomedical Materials Research, 2002

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The development of binary Mg-Ca alloys for use as biodegradable materials within bone. (2008, background): “The abundant magnesium ions released into the culture medium by the corrosion of Mge1Ca alloy might contribute to the increased cell viability since they were found to simulate the integrin-mediated osteoblast response by facilitating the interaction of integrins with their cognate ligands [29,30].”
Biomedical Implants: Corrosion and its Prevention - A Review~!2009-12-22~!2010-01-20~!2010-05-25~! (2010, background): “Magnesium as a degradable implant material provides both biocompatibility and suitable mechanical properties in in vitro and in vivo studies and it has been shown that magnesium is suitable to be used for degradable implants as they exhibit good cell attachment and tissue growth [5, 66, 67].”
Research on an Mg-Zn alloy as a degradable biomaterial. (2010, background): “[45] found that magnesium ions could enhance the adhesion of human bone-derived cells (HBDC) and increased the levels of a5b1and b1-integrin receptors.”