Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation

By Ulrike Fiedler, Y. Reiss, Marion Scharpfenecker, V. Grunow, Stefanie Koidl, Gavin Thurston, N. Gale, M. Witzenrath, S. Rosseau, N. Suttorp and 5 more. Nature Medicine, 2006

989 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8d91539b65fa3aad76001dc253dbfd6750f42648

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. P. Scherer
2. Haiming Cao
3. M. Blüher

In Immunology

1. P. Scherer
2. Yu A. An
3. Gerhard Christofori
4. C. Crewe

In Molecular Biology

1. P. Scherer
2. Yu A. An
3. Gerhard Christofori
4. C. Crewe
5. Ernesta Fagiani
6. R. Weinberg
7. D. Hanahan

Citations in the corpus

• The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. (2017, positive): “ANG-2 binds the endothelial cell RTK Tie2, activating endothelial cell migration and proliferation, but also initiating an NF-κB–dependent inflammatory signaling cascade (59).”
• Angiopoietins in angiogenesis. (2013, background): “Examples are VEGF-A and angiopoietins: both are critical in angiogenesis as well as in the recruitment of inflammatory cells [17–20].”