A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes.

By V. Rostovtsev, L. Green, Valery Fokin, K. Sharpless. Angewandte Chemie, 2002

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Contemporary strategies for peptide macrocyclization. (2011, background): “Recently, the groups of Meldal and Sharpless have developed a highly regioselective variant to generate a 1,4-disubstitution pattern that is catalysed by copper( I ) under mild condition”
Cylindrical molecular brushes: Synthesis, characterization, and properties (2008, methodology): “By employing highly efficient copper(I)-catalyzed azide–alkyne coupling reactions [119,120] commonly classified as a form of ‘‘click chemistry’’ [121] postpolymerization modification reactions have been observed to proceed to high conversion [122–126].”
POLYMER NANOCOMPOSITES BASED ON FUNCTIONALIZED CARBON NANOTUBES (2010, methodology): “The triazole is used s a rigid linker that can mimic the atom placement and lectronic properties of a peptide bond without the same usceptibility to hydrolytic cleavage [153,154], as shown in cheme 2.”