Evidence of a healthy volunteer effect in the prostate, lung, colorectal, and ovarian cancer screening trial.
By P. Pinsky, A. B. Miller, B. S. Kramer, Timothy R. Church, Douglas J. Reding, P. C. Prorok, E. P. Gelmann, Robert E. Schoen, S. Buys, Richard B. Hayes and 1 more. 2007
227 citations recorded by the source corpus.
Subfields: Economics and Econometrics, Oncology, Public Health, Environmental and Occupational Health
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Citations in the corpus
- Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population (2017, neutral): “Further follow-up is required to determine whether this “healthy volunteer effect” attenuates over time (owing to the development of chronic disease as the cohort ages), a phenomenonwhich has been observed in previous studies (18, 20, 32).”
- Prostate cancer screening in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of follow-up. (2012, background): “(4) seems questionable, because the cohort was relatively healthy to start with (18) and because those men in the 1.”
- Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials (2011, background): “However, volunteers participating in trials evaluating preventive interventions such as screening are on average healthier than the general population [1-3].”
- Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening (2011, unknown): “First, as is possible in any clinical study, the findings may be affected by the “healthy-volunteer” effect, which can bias results such that they are more favorable than those that will be observed when the intervention is implemented in the community.(24) The role of this bias in our results canno”
- Vitamins C and E: Beneficial effects from a mechanistic perspective (2011, background): “placebo group who routinely consume dietary levels of 15 mg αtocopherol are not likely to benefit from supplements and that the “healthy volunteer effect” [208] likely precludes finding a benefit for vitamin E in chronic disease prevention if the subjects are already well nourished with respect to α”