Age, neuropathology, and dementia.

By G. Savva, S. Wharton, P. Ince, G. Forster, F. Matthews, Carol Brayne. New England Journal of Medicine, 2009

893 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Preclinical Alzheimer’s disease: Definition, natural history, and diagnostic criteria (2016, background): “Aging may also have an impact on other biomarkers as pathologic features of AD [125].”
The changing prevalence and incidence of dementia over time — current evidence (2017, background): “degree of neuropathology, as well as considerable overlap of pathological features in people with and without dementia.(78,79) The new techniques for defining brain pathology and ‘normal’ function must be grounded through research within contemporary populations in order to understand the underlying”
Impact of multiple pathologies on the threshold for clinically overt dementia (2017, methodology): “Analyses from the MRC-CFAS and the MAP/ROS cohort also showed decreasing association between AD pathology and clinical dementia with increasing age [55, 109].”