The biogenesis, biology and characterization of circular RNAs

By L. Kristensen, M. S. Andersen, L. V. W. Stagsted, K. K. Ebbesen, T. B. Hansen, Jørgen Kjems. Nature reviews genetics, 2019

3,823 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8a8dd6cdcc06f1c8eabd9b88ceeb20ca020830ef

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In Cancer Research

1. Wanying Wu
2. Peifeng Ji
3. Fangqing Zhao

In Molecular Biology

1. Wanying Wu
2. Peifeng Ji
3. Benjamin J. Blencowe
4. Fangqing Zhao
5. A. Ren
6. Jernej Ule

Citations in the corpus

• Recent advances in RNA structurome (2022, background): “splicing called back splicing has been shown to be the fundamental mechanism for generating circular RNAs (Kristensen et al., 2019).”
• Circular RNA: metabolism, functions and interactions with proteins (2020, background): “CircRNA is generated by a special alternative splicing manner termed backsplicing, in which the 3′-end of an exon ligates to the 5′-end of its own or an upstream exon through a 3′,5′phosphodiester bond, forming a closed structure with a back-splicing junction site [7, 8, 26].”
• CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes (2020, background): “The circRNAs have been demonstrated to act as sponges for miRNAs or RBPs and have been thus predicted to function as the post-transcriptional regulators of gene expression [49].”
• The bioinformatics toolbox for circRNA discovery and analysis (2020, background): “It has been demonstrated that integration of different circRNA identification tools can reduce the false-positive rate [13, 77, 78].”
• Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution. (2019, methodology): “Similarly, methods for the transcriptome-wide mapping of spliceosomal assembly and RNARNA contacts, including both intra- and inter-molecular contacts, will be important for understanding how RNA structures regulate the formation of functional RNP complexes and the availability of splice sites or th”