Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A
By M. Verheij, C. de Graaf, Gerdien E. de Kloe, S. Nijmeijer, H. Vischer, R. Smits, O. Zuiderveld, Saskia Hulscher, Linda Silvestri, A. J. Thompson and 4 more. 2011
34 citations recorded by the source corpus.
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Subfields: Molecular Biology, Radiology, Nuclear Medicine and Imaging, Computational Chemistry & Drug Discovery
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In Molecular Biology
In Radiology, Nuclear Medicine and Imaging
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Citations in the corpus
- A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System Targets (2015, background): “That knowledge could guide target specificity by extending the fragment to favor the target-selective interactions (42).”