Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial.

By H. Ghofrani, R. Wiedemann, F. Rose, R. Schermuly, H. Olschewski, N. Weissmann, A. Gunther, D. Walmrath, W. Seeger, F. Grimminger. The Lancet, 2002

804 citations recorded by the source corpus.

Subfields: Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/8997af25f28779d3c0b3e5f9457bd1a24e816706

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In Pulmonary and Respiratory Medicine

1. H. Collard
2. G. Raghu
3. G. Simonneau

Citations in the corpus

• An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline. (2015, background): “(65, 67, 68), not including an adequate placebo (66, 68, 69), analyzing data retrospectively (68), or a combination of these methodologic concerns.”
• Pulmonary arterial hypertension (2013, background): “cial effect of PDE-5 inhibitors on vascular remodelling and vasodilatation [234,235].”
• Interstitial lung disease guideline (2008, neutral): “Однако вазодилатация легочных ар терий может оказывать негативное воздействие, усу губляя вентиляционно перфузионный дисбаланс [677] либо усиливая шунтирование [675] и, таким образом, утяжеляя гипоксемию при ИЗЛ.”
• Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond (2006, background): “In contrast to the infused prostanoid, selectivity for well-ventilated lung areas was demonstrated for sildenafil, resulting in an improvement, rather than deterioration, of gas exchange 143 .”
• Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (2015, background): “Sildenafil may also be useful in the setting of iNO therapy withdrawal, in postoperative PH,(368,372) or in the presence of PH related to chronic lung disease.(330) In a 16-week randomized, double-blind, placebo-controlled study of treatment naive children (Sildenafil in TreatmentNaïve Children, Age”