The comet assay: a method to measure DNA damage in individual cells

By P. Olive, J. Banáth. Nature Protocols, 2006

1,834 citations recorded by the source corpus.

Subfields: Cancer Research, Health, Toxicology and Mutagenesis, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8970d55363594f8b9a1ec2f46fef0f6c7810c1ca

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. David Hsu
2. Marie-Véronique Clément
3. Priya Thiagarajan
4. Benjamin M. Gyori
5. G. Venkatachalam
6. Jur van den Berg
7. Sertac Karaman

Citations in the corpus

• Ag2S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window (2012, neutral): “The comet assay has been considered as a well-established, simple, versatile, and sensitive tool to quantitatively assess DNA damage in individual cell populations.(28) The head is composed of intact DNA, while the tail consists of damaged or broken pieces of DNA.”
• OpenComet: An automated tool for comet assay image analysis (2014, methodology): “The comet assay, also known as single-cell gel electrophoresis (SCGE), is a simple, sensitive and reliable method for studying DNA damage induced by physical and chemical agents [5 – 7].”
• Growth Hormone Receptor Deficiency is Associated With a Major Reduction in Pro-aging Signaling, Cancer and Diabetes in Humans (2011, neutral): “Comet assay Comet assay was performed according to the method in (72) with the comet assay kit from Trevigen.”